370 research outputs found

    THE INTELLECTUAL CORE KNOWLEDGE OF THE MOBILE INFORMATION SYSTEM

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    O2O, an acronym of online-to-offline or vice versa, is a new business model blending online retailing with offline retailing. This new model improves an existing method of shopping by either integrating the online components for traditional shoppers or the traditional shopping for Internet or mobile shoppers. Few studies have examined consumers’ acceptance of new O2O business model. Therefore, this study attempts to investigate consumer acceptance of O2O business model from the status quo bias and habit perspectives that have been used to examine new system acceptance by past research. Using a sample data collected from 230 respondents, this study applies a structural equation model (SEM) to examine the relationships of the proposed research model. The results reveal that behavioural-based inertia positively impacts perceived ease of use and cognitive-based inertia positively impacts relative advantage, and consequently impacts consumers’ intention to use O2O shopping. In addition, subjective norm positively impacts perceived ease of use and relative advantage, and self-efficacy positively impacts perceived ease of use. Because O2O shopping is a consumer’s adoption of a new business model which involves information technologies and retailing services, this study thus provides in depth insights into enhancing the acceptance of both new information technologies and new business model. Particularly, inertia can facilitate consumers O2O shopping acceptance as opposed to inhibit new system acceptance found in past research. Perceived ease of use and relative advantage fully mediate the relationships between external variables (such as inertia, subjective norm, and self-efficacy) and O2O shopping intention. Implications are drawn for electronic commerce, mobile commerce, and retailing

    First R and I Lights and Their Photometric Analyses of GSC 02393-00680

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    We obtained complete RR and II light curves of GSC 02393-00680 in 2008 and analyzed them with the 2003 version of the W-D code. It is shown that GSC 02393-00680 is a W-type shallow contact binary system with a high mass ratio q=1.600q=1.600 and a degree of contact factor f=5.0f=5.0%(\pm1.3%). It will be a good example to check up on the TRO theory. A period investigation based on all available data suggests that the system has a small-amplitude period oscillation (A3=0.d0030A_3=0.^{d}0030; T3=1.92T_3=1.92years). This may indicate it has a moderate mass close third body, which is similar to XY Leo

    One-stage reconstruction of large lower lip defect and oral competence with free composite anterolateral thigh-tensor fasciae latae flap

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    SummaryReconstruction for a large lower lip defect is a challenge to reconstructive surgeons. The most challenging problem is to maintain oral competence and prevent sialorrhea. We present three cases of such a defect reconstructed with composite anterolateral thigh-tensor fascia lata free flaps in one stage. The patients reported in this communication had advanced squamous cell carcinoma in the lower lip. A large lower lip defect (>90%) resulted in each case from wide excision of the tumor. A composite anterolateral thigh-tensor fasciae latae free flap was used to reconstruct the defect and to restore the dynamic oral competence in one stage. A tensor fasciae latae sling was attached by two strips sutured together to the upper orbicularis oris muscle in the first case. The four-strip method, a modification of the method described by Serkan,1 was adopted in the second case. The upper two strips bilaterally sutured to the orbicularis oris muscles in a mode somewhat different from Serkan’s method. The tensor fasciae latae sling was attached by two strips sutured to the periosteum of both zygomatic eminences in the third case. The tensor fasciae latae sling of Case 1 failed with persistent sialorrhea. The second case had good oral competence and comprehensible speech ability without sialorrhea. The third case had an acceptable result before he was lost to follow-up. A composite anterolateral thigh-tensor fasciae latae free flap is a good choice for a large lower lip defect to achieve oral competence reconstruction in one stage. Simultaneous dynamic and static suspensions are suggested to maintain oral competence and prevent sialorrhea

    Adiponectin Gene Polymorphism Is Selectively Associated with the Concomitant Presence of Metabolic Syndrome and Essential Hypertension

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    OBJECTIVE: Cardiovascular risk increases with the presence of both metabolic syndrome (MetS) and hypertension (HTN). Although the adiponectin (ADIPOQ) gene has been reported to be involved in MetS, its association with HTN remained undetermined. This study aimed to investigate the association of ADIPOQ gene with the phenotypes of HTN and MetS. METHODS: A total of 962 participants from 302 families from the Taiwan young-onset hypertension genetic study were enrolled. Plasma adiponectin were measured, and association analysis was conducted by using GEE regression-based method. Another study, of 1448 unrelated participants, was conducted to replicate the association between ADIPOQ gene and variable phenotypes of MetS with or without HTN. RESULTS: Among 962 subjects from family samples, the lowest plasma adiponectin value was observed in MetS with HTN component (9.3±0.47 µg/ml) compared with hypertensives (13.4±0.74 µg /ml) or MetS without HTN (11.9±0.60 µg/ml, P<0.05). The SNP rs1501299 (G276T) in ADIPOQ gene was found associated with the presence of HTN in MetS (odds ratio for GG+GT vs. TT = 2.46; 95% CI: 1.14-5.3, p = 0.02), but not rs2241766 (T45G). No association of ADIPOQ gene with HTN alone or MetS without HTN was observed. The significant association of the SNP rs1501299 (G276T) with the phenotype of presence of HTN in MetS was confirmed (odds ratio for GG+GT vs. TT = 2.15; 95% CI: 1.1-4.3) in the replication study. CONCLUSIONS: ADIPOQ genetic variants were selectively and specifically associated with the concomitant presence of MetS and HTN, suggesting potential genetic linkage between MetS and HTN

    Toward Reproducing Network Research Results Using Large Language Models

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    Reproducing research results in the networking community is important for both academia and industry. The current best practice typically resorts to three approaches: (1) looking for publicly available prototypes; (2) contacting the authors to get a private prototype; and (3) manually implementing a prototype following the description of the publication. However, most published network research does not have public prototypes and private prototypes are hard to get. As such, most reproducing efforts are spent on manual implementation based on the publications, which is both time and labor consuming and error-prone. In this paper, we boldly propose reproducing network research results using the emerging large language models (LLMs). In particular, we first prove its feasibility with a small-scale experiment, in which four students with essential networking knowledge each reproduces a different networking system published in prominent conferences and journals by prompt engineering ChatGPT. We report the experiment's observations and lessons and discuss future open research questions of this proposal. This work raises no ethical issue

    High yield expression in a recombinant E. coli of a codon optimized chicken anemia virus capsid protein VP1 useful for vaccine development

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    <p>Abstract</p> <p>Background</p> <p>Chicken anemia virus (CAV), the causative agent chicken anemia, is the only member of the genus <it>Gyrovirus </it>of the <it>Circoviridae </it>family. CAV is an immune suppressive virus and causes anemia, lymph organ atrophy and immunodeficiency. The production and biochemical characterization of VP1 protein and its use in a subunit vaccine or as part of a diagnostic kit would be useful to CAV infection prevention.</p> <p>Results</p> <p>Significantly increased expression of the recombinant full-length VP1 capsid protein from chicken anemia virus was demonstrated using an <it>E. coli </it>expression system. The VP1 gene was cloned into various different expression vectors and then these were expressed in a number of different <it>E. coli </it>strains. The expression of CAV VP1 in <it>E. coli </it>was significantly increased when VP1 was fused with GST protein rather than a His-tag. By optimizing the various rare amino acid codons within the N-terminus of the VP1 protein, the expression level of the VP1 protein in <it>E. coli </it>BL21(DE3)-pLysS was further increased significantly. The highest protein expression level obtained was 17.5 g/L per liter of bacterial culture after induction with 0.1 mM IPTG for 2 h. After purification by GST affinity chromatography, the purified full-length VP1 protein produced in this way was demonstrated to have good antigenicity and was able to be recognized by CAV-positive chicken serum in an ELISA assay.</p> <p>Conclusions</p> <p>Purified recombinant VP1 protein with the gene's codons optimized in the N-terminal region has potential as chimeric protein that, when expressed in <it>E. coli</it>, may be useful in the future for the development of subunit vaccines and diagnostic tests.</p

    Impurity-induced in-gap state and Tc in sign-reversing s-wave superconductors: analysis of iron oxypnictide superconductors

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    The sign-reversing fully gapped superconducting state, which is expected to be realized in oxypnictide superconductors, can be prominently affected by nonmagnetic impurities due to the interband scattering of Cooper pairs. We study this problem based on the isotropic two-band BCS model: In oxypnictide superconductors, the interband impurity scattering II' is not equal to the intraband one II. In the Born scattering regime, the reduction in Tc is sizable and the impurity-induced density of states (DOS) is prominent if III\sim I', due to the interband scattering. Although impurity-induced DOS can yield a power-law temperature dependence in 1/T11/T_1, a sizable suppression in Tc is inevitably accompanied. In the unitary scattering regime, in contrast, impurity effect is very small for both Tc and DOS except at I=II=I'. By comparing theory and experiments, we expect that the degree of anisotropy in the s±s_\pm-wave gap function strongly depends on compounds.Comment: 16 pages, 5 figures, to be published in New. J. Phy
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